中文摘要】 目的了解广西在校大学生精液质量现状,并对影响精液质量的因素进行分析。方法用计算机辅助精子分析(CASA)技术,检查广西19所高校217例志愿学生的精液参数。以2 ml≤精液量≤6 ml,精子密度≥20×106/ ml,(a + b)级精子≥50 %或a级精子≥25 %,精子活率≥60 %,畸形率≤30 %为参考标准,同时满足上述标准者为正常,没有达到上述任何一个标准者都为异常,按此标准将受试者分为正常组和异常组来统计调查结果;同时对前列腺液白细胞,精索静脉曲张,支原体、衣原体感染,ASAb进行检测,并对正常组和异常组的检出率进行比较;另外将精液量、精子密度和活率与国内文献报道的结果进行对比。结果217例志愿者的精液量、精子密度、精子活率、a + b级精子及a级精子分别为:(3.06±1.25)ml、(64.78±44.20)×106/ml、(49.30±18.24)%、(39.43±16.38)%及(27.40±15.58)%,其中正常组94例(43.3%),异常组123例(56.7%)。正常组精子的曲线速度(VCL)、路径速度(VAP)及直线速度(VSL)均大于22μm/s,VC...更多L、VAP、VSL及运动的直线性(LIN)、运动前向性(STR)、精子平均鞭打频率(BCF)、精子平均移动角度(MAD)均显著大于异常组( P < 0.05)。异常组中,38例精液量<2ml(30.89%), 17例精子密度异常(3.25%), 87例精子活率<60 %(70.73%);有97例精子活力异常(78.86%),64例精子正常形态率<70%(52.03%),未发现无精子症者。217例志愿者的精子的活率低于国内文献报道的结果;但精液量无统计学差异;精子密度同我国其他地区正常成年男性的水平比较存在地区性及时间性差异。前列腺液白细胞异常,精索静脉曲张,支原体、衣原体感染,ASAb(+)检出率分别为:41.5%、33.2%、19.4%、6%。精液异常组的前列腺液白细胞异常,精索静脉曲张,支原体、衣原体感染,ASAb(+)检出率明显高于精液正常组。结论广西地区大学生精液质量异常的情况以精子活率及活力低比较突出,其精子的活率明显低于国内不同地区文献报道的结果。广西地区大学生精子活率、活力低及精子运动能力减弱,可能与前列腺液白细胞异常,精索静脉曲张,支原体、衣原体感染,ASAb(+)有关。
【英文摘要】 Objective : To evaluate the semen quality of college students in Guangxi area at present, and analysis the influence factor .Methods : A computer assisted sperm analysis (CASA) was made of the sperm concentration, grade A sperm, grade B sperm, survival rate and movement parameters (VCL、VAP、VSL、LIN、STR) of 217 volunteers from 19 colleges in Guangxi area. The volunteers were divided into normal and abnormal groups according to the criteria (2ml≤Semen volume≤6ml, sperm concentration≥20×106/ml, grade A and B sperm≥50% or grade A sperm≥25%, sperm survival rate≥60%, sperm morphology≥70%). The results were compared with the data reported in China. While, The WBC in EPS, Varicocele, ureaplasma urealyticum、Chlamydia Trachomatis infection, ASAb positive were detected and compared the detection rate of the normal and abnormal groups.Results: Among the 217 volunteers, the sperm concentration was (64.78±44.20)×106/ ml , grade A + grade B sperm was (39.43±16.38) % , grade A sperm was (27.40±15.58)% ..., and the sperm survival rate was (49.30±18.24)%. The volunteers with normal semen accounted for 43.3 %(94/217) in contrast with abnormal 56.7% (123/217) . Among the 123 volunteers with abnormal semen, there were 97 (78.86%) with abnormal survival rate, 17(3.25%) with abnormal concentration, 87(70.73%) abnormal motility. No volunteers were azoospermia. Among the 94 volunteers with normal semen, the VCL、VAP and VSL were above 22μm/s, and the VCL、VAP、VSL、LIN and STR were significantly higher than those of the abnormal group (P<0.01). Moreover, the sperm concentration and the sperm viability rate in 217 volunteers, including 94 volunteers with normal semen, were lower than the data reported in China. The rate of Abnormal WBC in EPS, Varicocele, ureaplasma urealyticum、Chlamydia Trachomatis infection, ASAb positive were detected individually:41.5%、33.2%、19.4%、6%。and the rate of Abnormal WBC in EPS, Varicocele, ureaplasma urealyticum、Chlamydia Trachomatis infection, ASAb positive were significantly higher than that of normal sperm group. (P<0.01).Conclusions : Abnormalities in the semen quality of the college students in Guangxi area are decreased sperm motility and sperm survival rate mainly. Survival rate is significantly lower than the data reported in China. The lower sperm survival rate、sperm motility and exercise capacity of sperm of the college students in Guangxi area may be related to prostatic fluid leukocyte abnormalities, varicocele, mycoplasma、chlamydia infection, ASAb positive.
【中文关键词】 精液质量; 大学生; 广西
【英文关键词】 semen quality ; College students ; Guangxi